⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685414 | 0.76 | P2RX4 (0.33) | — | |
| SCHEMBL525220 | 0.74 | FBP1 (0.38) | — | |
| SCHEMBL5327434 | 0.74 | FBP1 (0.38) | — | |
| SCHEMBL7126113 | 0.74 | FBP1 (0.38) | — | |
| SCHEMBL1333409 | 0.71 | — | — | |
| SCHEMBL5609875 | 0.71 | FBP1 (0.32) | — | |
| SCHEMBL1518186 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL10784064 | 0.69 | — | — | |
| SCHEMBL150348 | 0.69 | — | — | |
| SCHEMBL17178422 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113981020-A | Method for synthesizing lobeline hydrochloride intermediate by enzymatic chiral reduction | 江苏恒盛药业有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113981020-B | Method for synthesizing lobelin hydrochloride intermediate by enzyme catalytic chiral reduction | 江苏恒盛药业有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-10385065-B2 | Antibacterial compounds | REDX PHARMA PLC (GB) | 2019-08-20 | — | — | US | disclosed |
| EP-2967067-B1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2967067-B1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170158708-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-06-08 | — | — | US | disclosed |
| US-20170158708-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-06-08 | — | — | US | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| EP-2967067-A1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | Monsanto Technology LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-105163586-A | N-,C-disubstituted azoles for controlling nematode pests | MONSANTO TECHNOLOGY LLC | 2015-12-16 | — | — | CN | disclosed |
| EP-1641753-A1 | PROCESS FOR THE SYNTHESIS OF DISTAMYCIN AND DERIVATIVES THEREOF USING 1-METHYL-4-FORMYLAMINO-2-PYRROLECARBONYL CHLORIDE ITERATIVELY AS AN INTERMEDIATE | Naxospharma S.R.L. (IT) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004106301-A1 | PROCESS FOR THE SYNTHESIS OF DISTAMYCIN AND DERIVATIVES THEREOF USING 1-METHYL-4-FORMYLAMINO-2-PYRROLECARBONYL CHLORIDE ITERATIVELY AS AN INTERMEDIATE | NAXOSPHARMA S.R.L. (IT) | 2004-12-09 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-1076056-A1 | NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
| CN-1283617-A | Terazololine-one | NIPPON BAYER AGROCHEM K K (JP) | 2001-02-14 | — | — | CN | disclosed |
| CN-1132748-A | Tetrazolinones | BAYER AGROCHEM KK (JP) | 1996-10-09 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |