Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 2/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239818 | 0.93 | METTL3 (0.49) | METTL3CNR2TP53RXFP1MAPT | |
| SCHEMBL3239834 | 0.93 | METTL3 (0.49) | METTL3TP53RXFP1MAPTPOLB | |
| SCHEMBL3241266 | 0.90 | METTL3 (0.49) | METTL3TP53RXFP1MAPTLMNA | |
| SCHEMBL3245364 | 0.89 | METTL3 (0.48) | METTL3TP53RXFP1MAPTPOLB | |
| SCHEMBL1079181 | 0.89 | METTL3 (0.55) | METTL3CNR2TP53MAPTPOLB | |
| SCHEMBL1079178 | 0.89 | METTL3 (0.55) | METTL3CNR2TP53MAPTPOLB | |
| SCHEMBL3240262 | 0.88 | METTL3 (0.54) | METTL3TP53RXFP1MAPTLMNA | |
| SCHEMBL3241799 | 0.88 | METTL3 (0.54) | METTL3TP53RXFP1MAPTLMNA | |
| SCHEMBL3239732 | 0.87 | METTL3 (0.64) | METTL3TP53MAPT | |
| SCHEMBL3232549 | 0.87 | METTL3 (0.63) | METTL3TP53RXFP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |