Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242177 | 0.86 | LMNA (0.63) | L3MBTL1KDM4EALDH1A1LMNACYP2D6 | |
| SCHEMBL3242406 | 0.83 | GAA (0.74) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL10399489 | 0.83 | KDM4E (0.84) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3941164 | 0.79 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL16982016 | 0.77 | L3MBTL1 (0.68) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3388206 | 0.77 | L3MBTL1 (0.68) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3273909 | 0.77 | L3MBTL1 (0.68) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3388638 | 0.77 | L3MBTL1 (0.68) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL4026088 | 0.76 | L3MBTL1 (0.66) | L3MBTL1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3573068 | 0.76 | L3MBTL1 (0.61) | L3MBTL1KDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | CFTR, PKD1, PKD2 | L3MBTL1 3749/4885KDM4E 4565/4885ALDH1A1 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.