Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240062 | 0.86 | POLB (0.46) | POLBSMN1; SMN2 | |
| SCHEMBL3232380 | 0.84 | POLB (0.44) | POLBSMN1; SMN2 | |
| SCHEMBL3239528 | 0.83 | LMNA (0.47) | POLBSMN1; SMN2 | |
| SCHEMBL3240196 | 0.75 | — | — | |
| SCHEMBL27922304 | 0.75 | ACACB (0.57) | — | |
| SCHEMBL27922307 | 0.75 | ACACB (0.57) | — | |
| SCHEMBL3659616 | 0.72 | SMN1; SMN2 (0.58) | POLBSMN1; SMN2 | |
| SCHEMBL15116462 | 0.71 | MMP9 (0.51) | — | |
| SCHEMBL1321836 | 0.71 | SSTR4 (0.50) | — | |
| SCHEMBL7318985 | 0.70 | TACR3 (0.38) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |