Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239834 | 0.90 | METTL3 (0.49) | METTL3PLA2G4ATP53MAPTPOLB | |
| SCHEMBL1045212 | 0.89 | METTL3 (0.55) | METTL3TP53MAPTPOLBMETTL14 | |
| SCHEMBL1045214 | 0.89 | METTL3 (0.55) | METTL3TP53MAPTPOLBMETTL14 | |
| SCHEMBL3241799 | 0.88 | METTL3 (0.54) | METTL3PLA2G4ALTB4RTP53MAPT | |
| SCHEMBL3240262 | 0.88 | METTL3 (0.54) | METTL3PLA2G4ALTB4RTP53MAPT | |
| SCHEMBL3245364 | 0.87 | METTL3 (0.48) | METTL3PLA2G4ATP53MAPTPOLB | |
| SCHEMBL3232549 | 0.86 | METTL3 (0.63) | METTL3TP53MAPTPOLBCFD | |
| SCHEMBL3239818 | 0.86 | METTL3 (0.49) | METTL3TP53MAPTPOLBCFD | |
| SCHEMBL3239826 | 0.86 | METTL3 (0.50) | METTL3TP53MAPTPOLBCFD | |
| SCHEMBL3241266 | 0.85 | METTL3 (0.49) | METTL3TP53MAPTCFDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |