Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778163 | 0.86 | LMNA (0.37) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28046098 | 0.82 | LMNA (0.39) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL19433816 | 0.82 | CHRM1 (0.46) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8932169 | 0.79 | LMNA (0.36) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4060654 | 0.76 | LMNA (0.39) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4909335 | 0.74 | TP53 (0.39) | LMNATDP1TSHR | |
| SCHEMBL16280860 | 0.73 | LMNA (0.41) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL309124 | 0.73 | LMNA (0.41) | LMNACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL12657638 | 0.72 | — | — | |
| SCHEMBL12806444 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011769-A2 | SYSTEMS AND METHODS FOR SELECTIVE ALCOHOL PRODUCTION | NORTHWESTERN UNIVERSITY (US) | 2010-01-28 | — | — | WO | disclosed |