SCHEMBL309124

SCHEMBL309124

CCCC(O)C(O)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TSHR P16473 3/20 0.39
CYP3A4 P08684 2/20 0.39
NFKB1 P19838 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
HDAC7 Q8WUI4 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16280860 1.00 LMNA (0.41) LMNATDP1CHRM1AKR1A1CHRM3
SCHEMBL17414856 0.85 CA2 (0.41) LMNACYP3A4GPR84FDPSFFAR1
SCHEMBL14917632 0.81 GPR84 (0.52) LMNACYP3A4GPR84FFAR1
SCHEMBL10535132 0.79 CHRM1 (0.52) LMNATDP1CHRM1AKR1A1CHRM3
SCHEMBL10535143 0.79 CHRM1 (0.52) LMNATDP1CHRM1AKR1A1CHRM3
SCHEMBL260456 0.79 CHRM1 (0.52) LMNATDP1CHRM1AKR1A1CHRM3
SCHEMBL11882422 0.78
SCHEMBL15095825 0.78
SCHEMBL15095806 0.78
SCHEMBL18610928 0.77 METAP1 (0.40) TDP1CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103420793-A Method for separating and purifying butanol with polyvinylidene fluoride-dimethyl silicone polymer composite film UNIV DALIAN TECH 2013-12-04 CN claimed
CN-102787144-B Process for producing acetone and butanol by coupling biomass fermentation and pervaporation membrane INST PROCESS ENG CAS 2013-10-16 CN claimed
EP-2216680-B1 Fine particles and method for producing the same FUJIFILM CORP (JP) 2018-04-04 EP disclosed
US-20150336892-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC (US) 2015-11-26 US disclosed
CN-103420793-B The method of a kind of polyvinylidene difluoride (PVDF)-polydimethylsiloxane composite membrane separation and purification butanols DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-11-18 CN disclosed
EP-1770696-B1 OPTICAL RECORDING MEDIUM AND OPTICAL RECORDING METHOD OF OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO LTD (JP) 2014-12-17 EP disclosed
EP-2351650-B1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR INFORMATION RECORDING, AND AZO METAL COMPLEX DYE FUJI FILM CORP (JP) 2014-11-05 EP disclosed
US-8808824-B2 Optical information recording medium, method of recording information and azo metal complex dye FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
CN-103420793-A Method for separating and purifying butanol with polyvinylidene fluoride-dimethyl silicone polymer composite film UNIV DALIAN TECH 2013-12-04 CN disclosed
CN-102787144-B Process for producing acetone and butanol by coupling biomass fermentation and pervaporation membrane INST PROCESS ENG CAS 2013-10-16 CN disclosed
US-8517082-B2 Fine particles and method for producing the same FUJIFILM CORPORATION (JP) 2013-08-27 US disclosed
US-6524678-B2 Optical information recording medium; optical disks, digital video disks FUJI PHOTO FILM CO., LTD. (JP) 2003-02-25 US disclosed
US-20030017295-A1 Optical information recording medium FUJI PHOTO FILM CO., LTD. 2003-01-23 US disclosed
EP-1265234-A2 Optical information recording medium Fuji Photo Film Co., Ltd. (JP) 2002-12-11 EP disclosed
US-20020061381-A1 Optical information recording medium and information recording method FUJI PHOTO FILM CO., LTD. 2002-05-23 US disclosed
EP-1193699-A1 Optical information recording medium and information recording method FUJI PHOTO FILM CO., LTD. (JP) 2002-04-03 EP disclosed
US-20020006494-A1 Information recording medium and recording method FUJIFILM CORPORATION (JP) 2002-01-17 US disclosed
EP-1132901-A2 Information recording medium and recording method FUJI PHOTO FILM CO., LTD. (JP) 2001-09-12 EP disclosed
EP-1035540-A1 Optical information-recording medium and method for recording information FUJI PHOTO FILM CO., LTD. (JP) 2000-09-13 EP disclosed
US-3957745-A FLAVORING AND FRAGRANCE COMPOSITIONS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336892-A1 COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS SLC10A1, SLC10A2, FABP2 LMNA 3770/4885TDP1 4348/4885CHRM1 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.