Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.69 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249640 | 0.89 | ROCK2 (0.69) | ROCK2ROCK1 | |
| SCHEMBL3250445 | 0.85 | ROCK2 (0.63) | ROCK2ROCK1 | |
| SCHEMBL3255997 | 0.82 | ROCK2 (0.68) | ROCK2ROCK1 | |
| SCHEMBL3241837 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL3244196 | 0.82 | ROCK2 (0.74) | ROCK2ROCK1 | |
| SCHEMBL13391093 | 0.81 | ROCK2 (0.73) | ROCK2ROCK1 | |
| SCHEMBL13391053 | 0.81 | ROCK2 (0.64) | ROCK2ROCK1 | |
| SCHEMBL3245543 | 0.80 | ROCK2 (0.71) | ROCK2ROCK1 | |
| SCHEMBL3130996 | 0.79 | ROCK2 (0.82) | ROCK2ROCK1 | |
| SCHEMBL3249722 | 0.77 | ROCK2 (1.00) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |