SCHEMBL3242645

SCHEMBL3242645

O=C(NNC(=O)C(F)(F)S(=O)(=O)F)C(F)(F)S(=O)(=O)F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.32
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14524228 0.75 PPARA (0.35) ALDH1A1L3MBTL1CA2
SCHEMBL22072254 0.73 ALDH1A1 (0.41) ALDH1A1L3MBTL1CA2CA1TSHR
SCHEMBL19865401 0.72 MEN1 (0.59) ALDH1A1L3MBTL1CA2
SCHEMBL1054681 0.71 ALDH1A1 (0.39) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL28373 0.71 ALDH1A1 (0.60) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL6007570 0.70 CA1 (0.42) ALDH1A1L3MBTL1CA2CA1
SCHEMBL2352333 0.69 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL11077177 0.69 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL2351582 0.69 ALDH1A1 (0.57) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL19865186 0.69 ALDH1A1 (0.38) ALDH1A1L3MBTL1CA2CA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659026-B2 membrane electrodes; electrocatalysts; fuel cells E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-09 US disclosed
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells E. I. DU PONT DE NEMOURS AND COMPANY 2006-08-10 US disclosed
US-20060177717-A1 Fluorinated sulfonamide compounds and polymer electrolyte membranes prepared therefrom for use in electrochemical cells U.S. DEPARTMENT OF ENERGY 2006-08-10 US disclosed
WO-2005003081-A2 SULFONIMIDE CONTAINING COMPOUNDS AND THEIR USE IN POLYMER ELECTROLYTE MEMBRANES FOR ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO disclosed
WO-2005001979-A2 FLUORINATED SULFONAMIDE COMPOUNDS AND POLYMER ELECTROLYTE MEMBRANES PEPARED THEREFROM FOR USE IN ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells HCN2, KCNN2, NHERF1 ALDH1A1 3591/4885L3MBTL1 4278/4885CA2 12/4885
US-20060177717-A1 Fluorinated sulfonamide compounds and polymer electrolyte membranes prepared therefrom for use in electrochemical cells PEF1, NHERF1, PXMP4 ALDH1A1 3230/4885L3MBTL1 4271/4885CA2 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.