Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252520 | 0.89 | KDM4E (0.38) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3255160 | 0.87 | MAPT (0.38) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3245465 | 0.84 | ALDH1A1 (0.36) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3252606 | 0.84 | ALDH1A1 (0.36) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3254901 | 0.83 | KDM4E (0.38) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3250699 | 0.83 | KDM4E (0.39) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3251355 | 0.83 | ALDH1A1 (0.37) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4159935 | 0.80 | HTR1D (0.36) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3241913 | 0.80 | KDM4E (0.51) | RXFP1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3248789 | 0.79 | KDM4E (0.34) | RXFP1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | claimed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | claimed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | disclosed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | disclosed |