Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 10/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237241 | 0.94 | METTL3 (0.56) | METTL3EGFRCFDPYGLCNR1 | |
| SCHEMBL3246669 | 0.93 | METTL3 (0.54) | METTL3EGFRCFDCNR1CNR2 | |
| SCHEMBL1045152 | 0.92 | METTL3 (0.74) | METTL3EGFRCFDPLA2G4AMAPT | |
| SCHEMBL1045153 | 0.92 | METTL3 (0.74) | METTL3EGFRCFDPLA2G4AMAPT | |
| SCHEMBL3242587 | 0.88 | METTL3 (0.46) | METTL3EGFRCFDPYGLCNR1 | |
| SCHEMBL3245215 | 0.87 | METTL3 (0.71) | METTL3EGFRPLA2G4AMAPTGAA | |
| SCHEMBL1046014 | 0.86 | METTL3 (0.67) | METTL3CFDMAPTPYGLGAA | |
| SCHEMBL3243386 | 0.86 | METTL3 (0.46) | METTL3EGFRCFDPLA2G4APYGL | |
| SCHEMBL1046016 | 0.86 | METTL3 (0.67) | METTL3CFDMAPTPYGLGAA | |
| SCHEMBL3234873 | 0.85 | METTL3 (0.66) | METTL3EGFRPLA2G4AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |