Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243260 | 0.93 | METTL3 (0.61) | METTL3CFDEGFRCNR1CNR2 | |
| SCHEMBL1046233 | 0.92 | METTL3 (0.64) | METTL3CFDTP53RXFP1EGFR | |
| SCHEMBL3237241 | 0.92 | METTL3 (0.56) | METTL3CFDEGFRCNR1CNR2 | |
| SCHEMBL1046231 | 0.92 | METTL3 (0.64) | METTL3CFDTP53RXFP1EGFR | |
| SCHEMBL3245374 | 0.86 | METTL3 (0.41) | METTL3CFDRXFP1EGFRCD274 | |
| SCHEMBL3243387 | 0.86 | METTL3 (0.61) | METTL3CFDTP53RXFP1EGFR | |
| SCHEMBL3242587 | 0.86 | METTL3 (0.46) | METTL3CFDTP53EGFRCNR1 | |
| SCHEMBL3246661 | 0.86 | METTL3 (0.56) | METTL3TP53RXFP1 | |
| SCHEMBL1045153 | 0.85 | METTL3 (0.74) | METTL3CFDTP53EGFRCNR1 | |
| SCHEMBL1045152 | 0.85 | METTL3 (0.74) | METTL3CFDTP53EGFRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |