SCHEMBL324333

SCHEMBL324333

O=C1C=c2cc3c(cc2N1)=CC(=O)N3

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CCR6 P51684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4150644 0.72
SCHEMBL12276842 0.60 GSK3A (0.41) GSK3AGSK3BCCR6
SCHEMBL9587810 0.56 GSK3B (0.37) GSK3AGSK3BCCR6
Ethylene SCHEMBL6060832 0.54
SCHEMBL8874013 0.53 GSK3B (0.56) GSK3AGSK3BCCR6
SCHEMBL1304475 0.53
SCHEMBL678979 0.53
SCHEMBL1029298 0.53
SCHEMBL5030857 0.53
SCHEMBL7719413 0.51 GSK3A (0.32) GSK3AGSK3BCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287504-B2 Semiconducting polymers MERCK PATENT GMBH (DE) 2016-03-15 US disclosed
EP-2591038-B1 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2014-11-05 EP disclosed
US-20130175481-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-11 US disclosed
EP-2591038-A1 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2013-05-15 EP disclosed
WO-2012003918-A1 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2012-01-12 WO disclosed