Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239874 | 0.90 | LMNA (0.38) | ALDH1A1LMNAMAPTRXFP1CPT1A | |
| SCHEMBL3240157 | 0.89 | CPT1A (0.37) | ALDH1A1LMNAMAPTRXFP1CPT1A | |
| SCHEMBL1043493 | 0.88 | LMNA (0.52) | ALDH1A1LMNAKDM4EHTTMEN1 | |
| SCHEMBL3243303 | 0.85 | TP53 (0.38) | ALDH1A1LMNAMAPTRXFP1TP53 | |
| SCHEMBL3242661 | 0.85 | TP53 (0.36) | ALDH1A1LMNAKDM4EHTTMEN1 | |
| SCHEMBL3245273 | 0.85 | MAPT (0.41) | ALDH1A1LMNAKDM4EMAPTRAB9A | |
| SCHEMBL3246977 | 0.84 | TP53 (0.36) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL3234992 | 0.83 | LMNA (0.38) | ALDH1A1LMNAMAPTRXFP1TP53 | |
| SCHEMBL3239841 | 0.83 | TP53 (0.37) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL3237627 | 0.83 | TP53 (0.37) | ALDH1A1LMNAMAPTRXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |