Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924350 | 0.84 | EPHX1 (0.39) | EPHX1KDM4EALDH1A1EPHX2RAB9A | |
| SCHEMBL3243651 | 0.82 | EPHX1 (0.37) | EPHX1KDM4EALDH1A1EPHX2RAB9A | |
| SCHEMBL4565651 | 0.73 | CCNA2 (0.31) | — | |
| SCHEMBL2923876 | 0.73 | AURKA (0.52) | EPHX1ALDH1A1EPHX2RAB9A | |
| SCHEMBL2924353 | 0.71 | EPHX1 (0.40) | EPHX1KDM4EALDH1A1EPHX2RAB9A | |
| SCHEMBL16648548 | 0.60 | EPHX1 (0.60) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL14424445 | 0.59 | EPHX1 (0.68) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL13480593 | 0.58 | EPHX1 (0.72) | EPHX1KDM4EALDH1A1EPHX2RAB9A | |
| SCHEMBL966655 | 0.58 | EPHX1 (0.72) | EPHX1KDM4EALDH1A1EPHX2RAB9A | |
| SCHEMBL13480574 | 0.58 | EPHX1 (0.72) | EPHX1KDM4EALDH1A1EPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320531-B1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2010-09-08 | — | — | EP | claimed |