Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393367 | 0.84 | CCNA2 (0.34) | CCNA2CDK2CCNA1 | |
| SCHEMBL4565648 | 0.82 | — | — | |
| SCHEMBL3243655 | 0.73 | EPHX1 (0.38) | — | |
| SCHEMBL12393369 | 0.71 | CCNA2 (0.32) | CCNA2CDK2 | |
| SCHEMBL2606340 | 0.59 | ALOX5 (0.41) | — | |
| SCHEMBL2606357 | 0.59 | ALOX5 (0.41) | — | |
| SCHEMBL2924350 | 0.57 | EPHX1 (0.39) | CCNA2CDK2CCNA1 | |
| SCHEMBL2915971 | 0.56 | CCNA2 (0.47) | CCNA2CDK2CCNA1 | |
| SCHEMBL2606475 | 0.55 | ALOX5 (0.37) | — | |
| SCHEMBL2914606 | 0.53 | CCNA2 (0.42) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221632-A1 | Bicyclo-Pyrazoles and Pharmaceutical Compositions Comprising Them | PFIZER ITALIA S.R.L. (IT) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221632-A1 | Bicyclo-Pyrazoles and Pharmaceutical Compositions Comprising Them | MAP3K20, PLK2, PRKAA1 | CCNA2 1043/4885CDK2 70/4885CCNA1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.