SCHEMBL324369

SCHEMBL324369

O=C(O)c1cnc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29229113 0.98 HCAR2 (0.57)
Formaldehyde SCHEMBL27847261 0.96 HCAR2 (0.55)
SCHEMBL3701608 0.79
SCHEMBL1238343 0.79
SCHEMBL854956 0.79
SCHEMBL23850697 0.79 HCAR2 (0.38)
SCHEMBL472995 0.79 CSNK2A2 (0.42)
SCHEMBL1810308 0.78 HCAR2 (0.61)
SCHEMBL600887 0.77 HCAR2 (0.61)
SCHEMBL16198634 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 683 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586257-A Compound containing 2, 8-diazaspiro [4.5] decan-1-one skeleton and application thereof 中国药科大学 2024-02-23 CN claimed
CN-108350034-B Antimicrobial polymyxin derived compounds 莫纳什大学 2022-03-11 CN claimed
CN-110746511-B Method for preparing modified starch for papermaking sizing agent from broken rice leftover in rice production 安徽金太阳食品有限公司 2021-05-28 CN claimed
CN-110746511-A Method for preparing modified starch for papermaking sizing agent from broken rice leftover in rice production 安徽金太阳食品有限公司 2020-02-04 CN claimed
WO-2007138110-A2 COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY DEVGEN N.V. (BE) 2007-12-06 WO claimed
CN-119707952-B Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-122079899-A Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein 2026-05-26 CN disclosed
EP-4041730-B1 SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2026-05-13 EP disclosed
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES SEED THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-12594264-B2 Modulators of alpha-synuclein proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-04-07 US disclosed
EP-4704836-A1 HETEROAROMATIC INDOLESULFONAMIDES Seed Therapeutics, Inc (US) 2026-03-11 EP disclosed
US-12552757-B2 NRF2-activating compound SENJU PHARMACEUTICAL CO., LTD. (JP) 2026-02-17 US disclosed
US-5136042-A PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1992-08-04 US disclosed
EP-0377750-A1 PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES MITSUI CHEMICALS, INC. (JP) 1990-07-18 EP disclosed
US-4089865-A Certain thiazole compounds SYNTEX (U.S.A.) INC. (US) 1978-05-16 US disclosed
US-4064259-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4064135-A Certain thiazole-5-carboxamide compounds SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4064258-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4064257-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4001421-A THIAZOLE CARDIOVASCULAR AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-04 US disclosed