Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757566 | 0.83 | TTR (0.56) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL6242 | 0.82 | TTR (0.75) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL29363198 | 0.82 | TTR (0.75) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL30233642 | 0.82 | TTR (0.75) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL14511497 | 0.80 | TTR (0.46) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL10902168 | 0.80 | TTR (0.53) | TTRCYP1A2MEN1POLBKMT2A | |
| SCHEMBL11013439 | 0.80 | TTR (0.67) | TTRCYP1A2SNCACHATCDK2 | |
| Ammonia Solution, Strong SCHEMBL25312340 | 0.80 | TTR (0.72) | TTRCYP1A2SNCACHATCDK2 | |
| SCHEMBL127423 | 0.80 | TTR (0.72) | TTRCYP1A2SNCACHATCDK2 | |
| Sulfuric Acid SCHEMBL4071142 | 0.80 | TTR (0.72) | TTRCYP1A2SNCACHATCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179085-B2 | METHOD FOR SEQUENCING NUCLEIC ACID MOLECULES | CORNELL RES FOUNDATION INC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-1179085-B1 | METHOD FOR SEQUENCING NUCLEIC ACID MOLECULES | CORNELL RES FOUNDATION INC (US) | 2010-05-05 | — | — | EP | disclosed |