Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244193 | 0.80 | TTR (0.55) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8779847 | 0.80 | TTR (0.47) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6911279 | 0.79 | TTR (0.64) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL5403732 | 0.78 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL7513876 | 0.78 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL31504547 | 0.78 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL998621 | 0.78 | CA2 (0.67) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL3379116 | 0.78 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL7514455 | 0.78 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL35949 | 0.78 | HTR6 (0.60) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381590-B1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2007-06-20 | — | — | EP | disclosed |