Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | CD40 | P25942 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120265 | 0.89 | CD40 (0.50) | TTRKDM4EMAPTCYP1A2POLB | |
| SCHEMBL6073527 | 0.86 | CASP6 (0.60) | TTRKDM4EMAPTCYP1A2POLB | |
| SCHEMBL6244552 | 0.83 | CD40 (0.49) | TTRCYP1A2CASP6MEN1KMT2A | |
| SCHEMBL10900413 | 0.83 | TTR (0.47) | TTRKDM4EMAPTNPY5RCYP1A2 | |
| SCHEMBL17327886 | 0.82 | PTPN1 (0.48) | TTRNPY5RCYP1A2CASP6CD40 | |
| SCHEMBL1339026 | 0.82 | NPC1 (0.62) | CYP1A2POLBRAB9ACD40CD40LG | |
| SCHEMBL4353216 | 0.82 | MAPT (0.56) | KDM4EMAPTCYP1A2POLBSMN1; SMN2 | |
| SCHEMBL7757566 | 0.81 | TTR (0.56) | TTRMAPTCYP1A2POLBCASP6 | |
| SCHEMBL12994192 | 0.81 | TTR (0.49) | TTRCYP1A2POLBCASP6KMT2A | |
| SCHEMBL11441738 | 0.81 | ALDH1A1 (0.47) | TTRMAPTNPY5RCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599203-A | Multisulfonated naphthalene ureas useful as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4591604-A | Method of inhibiting the complement system by administering multisulfonated naphthalene ureas | AMERICAN CYANAMID COMPANY (US) | 1986-05-27 | — | — | US | disclosed |