Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242238 | 0.92 | F10 (0.39) | F10DGAT2KDM4EALDH1A1LMNA | |
| SCHEMBL3246178 | 0.90 | F10 (0.43) | F10F2SSTR5 | |
| SCHEMBL3508057 | 0.90 | F10 (0.45) | F10DGAT2KDM4EALDH1A1LMNA | |
| SCHEMBL12311487 | 0.84 | F10 (0.46) | F10KDM4EALDH1A1LMNAF2 | |
| SCHEMBL3245401 | 0.83 | F10 (0.41) | F10KDM4EALDH1A1F2 | |
| SCHEMBL3507659 | 0.83 | F10 (0.43) | F10DGAT2KDM4EALDH1A1LMNA | |
| SCHEMBL3508891 | 0.81 | F10 (0.45) | F10F2 | |
| SCHEMBL3246184 | 0.79 | F10 (0.38) | F10DGAT2KDM4EALDH1A1LMNA | |
| SCHEMBL3507730 | 0.74 | F10 (0.45) | F10F2SSTR5 | |
| SCHEMBL3506367 | 0.73 | F10 (0.43) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029546-B1 | ARYL-SUBSTITUTED HETEROCYCLES, AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-28 | — | — | EP | disclosed |