SCHEMBL3244447

SCHEMBL3244447

CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.44
▸ NPY5R Q15761 5/20 0.38
▸ NPY4R P50391 5/20 0.38
▸ NPY1R P25929 4/20 0.38
▸ NPY2R P49146 2/20 0.38
▸ FURIN P09958 2/20 0.37
▸ ROCK2 O75116 1/20 0.36
▸ MAP1LC3B Q9GZQ8 2/20 0.35
▸ NMT2 O60551 1/20 0.35
▸ NMT1 P30419 1/20 0.35
▸ HTT P42858 1/20 0.34
▸ ITGB1 P05556 1/20 0.34
▸ ITGA5 P08648 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15246622 1.00 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL21416485 1.00 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL16266184 1.00 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL24848129 0.99 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL23286101 0.97 FAP (0.42) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL18244334 0.94 FAP (0.40) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL18244335 0.94 FAP (0.40) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL22952275 0.94 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL24520454 0.94 FAP (0.47) FAPNPY5RNPY4RNPY1RNPY2R
SCHEMBL20808481 0.94 FAP (0.44) FAPNPY5RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2026-05-28 — — US claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 — — WO claimed
WO-2026098621-A1 ENGINEERED ANTIBODY WITH SITE-SPECIFIC CONJUGATION, ANTIBODY-DRUG CONJUGATE, AND APPLICATION THEREOF 百力司康生物医药(杭州)有限公司 2026-05-15 — — WO claimed
WO-2026090578-A1 CDH17-BINDING ANTIBODIES AND METHODS OF USE THEREOF Antharis Therapeutics Inc. (US) 2026-04-30 — — WO claimed
WO-2026090567-A1 FLT3-BINDING ANTIBODIES AND METHODS OF USE THEREOF Antharis Therapeutics Inc. (US) 2026-04-30 — — WO claimed
US-20260115303-A1 CDH17-BINDING ANTIBODIES AND METHODS OF USE THEREOF ANTHARIS THERAPEUTICS INC (US) 2026-04-30 — — US claimed
EP-4729617-A1 APTAMER TARGETING CD25, DRUG CONJUGATE COMPRISING SAME, AND USE THEREOF Aptamer Sciences Inc. (KR) 2026-04-22 — — EP claimed
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2026-04-21 — — US claimed
EP-4725966-A1 HUMAN EPIDERMAL GROWTH FACTOR 3 ANTIBODY, PREPARATION METHOD THEREFOR, AND USE THEREOF SHANGHAI RUOTUO BIOSCIENCES CO., LTD. (CN) 2026-04-15 — — EP claimed
EP-4720134-A1 ANTI-CEACAM5/6 DUAL-BINDING ANTIBODIES Nona Biosciences (Suzhou) Co., Ltd. (CN) 2026-04-08 — — EP claimed
US-20220251197-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2022-08-11 — — US claimed
CN-111617250-B Multi-ligand drug couplet and application thereof 同宜医药(苏州)有限公司 2022-07-01 — — CN claimed
CN-114685668-A Human GPC3 monoclonal antibody and conjugate thereof 石药集团巨石生物制药有限公司 2022-07-01 — — CN claimed
WO-2022111616-A1 ANTI-CLDN18.2 ANTIBODY, DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 石药集团巨石生物制药有限公司 2022-06-02 — — WO claimed
WO-2022105881-A1 ANTI-CD73 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105878-A1 MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105879-A1 ANTI-CD276 ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
WO-2022105873-A1 ENGINEERED ANTIBODY, ANTIBODY-DRUG CONJUGATE, AND USE THEREOF Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2022-05-27 — — WO claimed
CN-114191428-A Eribulin-based antibody-drug conjugates and methods of use 卫材研究发展管理有限公司 2022-03-18 — — CN claimed
US-20220023437-A1 HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2022-01-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605457-B2 Modified EGFR antibody with reduced affinity, drug conjugate, and use thereof EGFR, ERBB2, IGSF11 FAP 4822/4885NPY5R 2241/4885NPY4R 954/4885
US-20260115303-A1 CDH17-BINDING ANTIBODIES AND METHODS OF USE THEREOF CDH1, H1-3, H1-2 FAP 4033/4885NPY5R 1169/4885NPY4R 1470/4885
US-20220023437-A1 HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE CD99, CD79B, CD47 FAP 2452/4885NPY5R 4310/4885NPY4R 4780/4885
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE H1-10, IGSF11, CD99 FAP 4682/4885NPY5R 2450/4885NPY4R 2837/4885
US-20220251197-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE CD99, CD79B, CD47 FAP 3575/4885NPY5R 4516/4885NPY4R 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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