Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244619 | 1.00 | DNM1 (0.56) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL4602895 | 0.92 | DNM1 (0.50) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL11230062 | 0.92 | DNM1 (0.50) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL4602294 | 0.92 | DNM1 (0.50) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL4603220 | 0.92 | DNM1 (0.50) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL4603260 | 0.92 | DNM1 (0.50) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL21092276 | 0.86 | DNM1 (0.45) | DNM1PLA2G1BPLA2G2ALMNA | |
| SCHEMBL20299940 | 0.84 | TSHR (0.47) | DNM1TSHRLMNAOPRM1 | |
| SCHEMBL196549 | 0.84 | TSHR (0.47) | DNM1TSHRLMNAOPRM1 | |
| SCHEMBL4556813 | 0.84 | TSHR (0.47) | DNM1TSHRLMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748798-B1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB (US) | 2010-05-05 | — | — | EP | claimed |