Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484589 | 0.89 | DNM1 (0.46) | DNM1GPR84SPHK1FFAR1LMNA | |
| SCHEMBL1934507 | 0.86 | ALDH1A1 (0.43) | FFAR1LMNA | |
| SCHEMBL17791303 | 0.86 | ALDH1A1 (0.43) | FFAR1LMNA | |
| SCHEMBL21235445 | 0.86 | ALDH1A1 (0.43) | FFAR1LMNA | |
| SCHEMBL3244458 | 0.86 | DNM1 (0.56) | DNM1LMNAPLA2G1BPLA2G2A | |
| SCHEMBL3244619 | 0.86 | DNM1 (0.56) | DNM1LMNAPLA2G1BPLA2G2A | |
| SCHEMBL24372389 | 0.86 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNA | |
| SCHEMBL24936070 | 0.85 | MAPK1 (0.49) | DNM1LMNA | |
| SCHEMBL22223952 | 0.81 | DNM1 (0.40) | DNM1 | |
| SCHEMBL24936083 | 0.81 | DNM1 (0.49) | DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494963-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | The University of British Columbia (CA) | 2019-06-12 | — | — | EP | disclosed |