Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892967 | 0.95 | TERT (0.33) | TERTTOP1 | |
| SCHEMBL8478754 | 0.86 | TOP1 (0.30) | TOP1 | |
| SCHEMBL8476021 | 0.86 | TOP1 (0.30) | TOP1 | |
| SCHEMBL8473370 | 0.80 | — | — | |
| SCHEMBL6002474 | 0.78 | GABRA1 (0.30) | — | |
| SCHEMBL8473510 | 0.77 | STAT3 (0.45) | — | |
| SCHEMBL8001501 | 0.76 | TERT (0.37) | TERTTOP1 | |
| SCHEMBL8478787 | 0.72 | — | — | |
| SCHEMBL8476024 | 0.72 | AR (0.31) | — | |
| SCHEMBL8474514 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469001-B1 | Corroles, including chiral derivatives and the use thereof | TECHNION RES & DEV FOUNDATION (IL) | 2010-05-05 | — | — | EP | disclosed |
| EP-1117666-B1 | PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF | TECHNION RES & DEV FOUNDATION (IL) | 2004-12-01 | — | — | EP | disclosed |
| EP-1469001-A1 | Corroles, including chiral derivatives and the use thereof | Technion Research & Development Foundation Limited (IL) | 2004-10-20 | — | — | EP | disclosed |
| US-6541628-B1 | Solvent-free condensation of an aldehyde with a pyrrole derivative to form corroles, salts or complexes | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2003-04-01 | — | — | US | disclosed |
| EP-1117666-A2 | PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF | Technion Research & Development Foundation Limited (IL) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018771-A2 | PROCESS FOR THE PREPARATION OF CORROLES AND SEVERAL SUCH NEW COMPOUNDS, INCLUDING CHIRAL DERIVATIVES, AND THE USE THEREOF | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2000-04-06 | — | — | WO | disclosed |