Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241309 | 0.88 | ROCK2 (0.49) | ROCK2ROCK1MYLK4CYP2C9CDC42BPA | |
| SCHEMBL3250294 | 0.82 | ROCK2 (0.54) | ROCK2ROCK1MYLK4CYP3A4CYP2D6 | |
| SCHEMBL3239739 | 0.80 | ROCK2 (0.53) | ROCK2ROCK1MYLK4CYP3A4CYP2D6 | |
| SCHEMBL3250449 | 0.78 | ROCK2 (0.56) | ROCK2ROCK1MYLK4CYP2C9CDC42BPA | |
| SCHEMBL3248444 | 0.77 | ROCK2 (0.55) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3242416 | 0.74 | ROCK2 (0.55) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3244746 | 0.72 | ROCK2 (0.57) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3237795 | 0.72 | ROCK2 (0.47) | ROCK2ROCK1MYLK4CYP3A4CYP2D6 | |
| SCHEMBL3242878 | 0.72 | ROCK2 (0.58) | ROCK2ROCK1CYP2C9CDC42BPA | |
| SCHEMBL3124374 | 0.71 | ROCK2 (0.64) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |