⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333133 | 0.72 | LMNA (0.46) | — | |
| SCHEMBL5805414 | 0.64 | LMNA (0.38) | — | |
| SCHEMBL25763520 | 0.61 | TSHR (0.48) | — | |
| SCHEMBL13615583 | 0.61 | TSHR (0.48) | — | |
| SCHEMBL17642560 | 0.59 | — | — | |
| SCHEMBL17665115 | 0.57 | — | — | |
| SCHEMBL17352445 | 0.57 | — | — | |
| SCHEMBL20457961 | 0.56 | ALOX15 (0.39) | — | |
| SCHEMBL18746008 | 0.55 | — | — | |
| SCHEMBL23224418 | 0.54 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009007-A1 | Non-covalent modification of microparticles and process of preparing same | BAXTER INTERNATIONAL INC. (US) | 2010-01-14 | — | — | US | disclosed |
| WO-2010006194-A2 | NON-COVALENT MODIFICATION OF MICROPARTICLES AND PROCESS OF PREPARING SAME | BAXTER INTERNATIONAL INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20060260777-A1 | SURFACE-MODIFIED MICROPARTICLES AND METHODS OF FORMING AND USING THE SAME | BAXTER HEALTHCARE S.A. (CH) | 2006-11-23 | — | — | US | disclosed |