Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 2/20 | 0.49 |
| ▸ | CFD | P00746 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239561 | 0.96 | METTL3 (0.49) | METTL3CFDMAPTGAAMCL1 | |
| SCHEMBL3242335 | 0.94 | METTL3 (0.49) | METTL3CFDMAPTGAAMCL1 | |
| SCHEMBL3241143 | 0.92 | METTL3 (0.51) | METTL3MAPTGAATP53RXFP1 | |
| SCHEMBL3245174 | 0.90 | METTL3 (0.60) | METTL3MAPTGAATP53 | |
| SCHEMBL1043836 | 0.90 | METTL3 (0.58) | METTL3CFDMAPTGAATP53 | |
| SCHEMBL3245303 | 0.88 | METTL3 (0.54) | METTL3CFDMAPTGAATP53 | |
| SCHEMBL3237348 | 0.87 | METTL3 (0.45) | METTL3 | |
| SCHEMBL3243820 | 0.87 | METTL3 (0.48) | METTL3MAPTGAATP53RXFP1 | |
| SCHEMBL1061396 | 0.86 | METTL3 (0.57) | METTL3MAPTGAATP53RXFP1 | |
| SCHEMBL3239930 | 0.85 | METTL3 (0.47) | METTL3CFDMAPTGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |