Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078255 | 0.92 | METTL3 (0.52) | METTL3PTGER1SCN9AFABP4CNR2 | |
| SCHEMBL3245198 | 0.87 | METTL3 (0.49) | METTL3 | |
| SCHEMBL3241143 | 0.86 | METTL3 (0.51) | METTL3P2RX7 | |
| SCHEMBL3239561 | 0.86 | METTL3 (0.49) | METTL3 | |
| SCHEMBL3241182 | 0.86 | METTL3 (0.35) | METTL3PTGER1SCN9AFABP4 | |
| SCHEMBL3242335 | 0.85 | METTL3 (0.49) | METTL3CNR2 | |
| SCHEMBL3245174 | 0.85 | METTL3 (0.60) | METTL3 | |
| SCHEMBL3245303 | 0.83 | METTL3 (0.54) | METTL3P2RX7 | |
| SCHEMBL3239764 | 0.83 | METTL3 (0.45) | METTL3 | |
| SCHEMBL3243820 | 0.81 | METTL3 (0.48) | METTL3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |