Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253968 | 0.90 | PKM (0.49) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3246232 | 0.88 | MAPT (0.46) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3251025 | 0.87 | TP53 (0.45) | LMNAKMT2AALPLTP53MAPT | |
| SCHEMBL3246156 | 0.87 | MAPT (0.45) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3249059 | 0.87 | MAPT (0.47) | LMNAKMT2ATP53MAPTMAPK1 | |
| SCHEMBL3251809 | 0.86 | MAPT (0.44) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3254878 | 0.86 | PKM (0.52) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3249389 | 0.86 | ALDH1A1 (0.52) | LMNAKMT2ATP53MAPTTHRB | |
| SCHEMBL3243020 | 0.85 | PKM (0.48) | LMNAKMT2ATP53MAPTMAPK1 | |
| SCHEMBL3249858 | 0.85 | HSD17B10 (0.42) | LMNAKMT2ATP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |