Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | CFD | P00746 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245215 | 0.91 | METTL3 (0.71) | METTL3PLA2G4AMAPTGAAEGFR | |
| SCHEMBL3243387 | 0.90 | METTL3 (0.61) | METTL3PLA2G4ACFDMAPTGAA | |
| SCHEMBL1045205 | 0.89 | METTL3 (0.68) | METTL3PLA2G4ACFDMAPTGAA | |
| SCHEMBL1045204 | 0.89 | METTL3 (0.68) | METTL3PLA2G4ACFDMAPTGAA | |
| SCHEMBL3240262 | 0.86 | METTL3 (0.54) | METTL3PLA2G4ACFDMAPTGAA | |
| SCHEMBL3241799 | 0.86 | METTL3 (0.54) | METTL3PLA2G4ACFDMAPTGAA | |
| SCHEMBL3241842 | 0.83 | METTL3 (0.83) | METTL3PLA2G4AMAPTGAAEGFR | |
| SCHEMBL3243274 | 0.82 | METTL3 (0.71) | METTL3CFDMAPTEGFRTP53 | |
| SCHEMBL3234873 | 0.82 | METTL3 (0.66) | METTL3PLA2G4AMAPTGAAEGFR | |
| SCHEMBL3242581 | 0.81 | METTL3 (0.72) | METTL3PLA2G4AMAPTGAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |