Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238154 | 0.95 | MAPK1 (0.38) | MAPK1KDM4EHTTALDH1A1PDE4D | |
| SCHEMBL3232029 | 0.91 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1GRM2L3MBTL1 | |
| SCHEMBL3236033 | 0.88 | MAPK1 (0.38) | MAPK1KDM4EALDH1A1GRM2KMT2A | |
| SCHEMBL3232108 | 0.83 | MAPK1 (0.40) | MAPK1KDM4EALDH1A1PDE4DGRM2 | |
| SCHEMBL3237508 | 0.81 | MAPK1 (0.36) | MAPK1HTR2AHTR2CKDM4EHTT | |
| SCHEMBL3226317 | 0.80 | MAPK1 (0.38) | MAPK1ALDH1A1BRD4 | |
| SCHEMBL10509423 | 0.79 | MAPK1 (0.44) | MAPK1KDM4EALDH1A1GRM2L3MBTL1 | |
| SCHEMBL3239393 | 0.79 | HRH3 (0.45) | KDM4E | |
| SCHEMBL3233897 | 0.78 | MAPK1 (0.38) | MAPK1GRM2METKMT2AMEN1 | |
| SCHEMBL3264017 | 0.73 | MAPK1 (0.40) | MAPK1KDM4EGRM2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |