Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235712 | 0.95 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL3230952 | 0.87 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL3236033 | 0.80 | MAPK1 (0.38) | KDM4E | |
| SCHEMBL3232029 | 0.80 | MAPK1 (0.46) | KDM4E | |
| SCHEMBL3245750 | 0.79 | MAPK1 (0.36) | KDM4E | |
| SCHEMBL3236422 | 0.78 | HRH3 (0.40) | HRH3 | |
| SCHEMBL3227312 | 0.77 | GRM5 (0.35) | KDM4E | |
| SCHEMBL3232108 | 0.75 | MAPK1 (0.40) | KDM4E | |
| SCHEMBL3240767 | 0.75 | HRH3 (0.39) | HRH3 | |
| SCHEMBL3240771 | 0.71 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |