SCHEMBL3245928

SCHEMBL3245928

O=[PH]1Oc2ccccc2-c2ccccc21.Oc1ccc(Cc2ccc(O)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
KEAP1 Q14145 1/20 0.37
NR1H3 Q13133 1/20 0.34
POLB P06746 1/20 0.34
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
ELANE P08246 1/20 0.33
GSK3B P49841 2/20 0.33
STK17B O94768 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL14648293 0.91 HDAC3 (0.37) ESR1ESR2POLBSTK17BHDAC3
Phenol SCHEMBL28577587 0.86 TDP1 (0.38) STK17BHDAC3HDAC4HDAC1HDAC7
SCHEMBL29173934 0.82 LMNA (0.44) ESR1ESR2POLBNPC1RAB9A
SCHEMBL29363087 0.82 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL30781 0.82 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL29395467 0.82 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL31183036 0.81 HSP90AA1 (0.34) MAPK1TDP1
SCHEMBL28437933 0.81 HSP90AA1 (0.34) MAPK1TDP1
Bromide SCHEMBL28619414 0.81 HSP90AA1 (0.34) MAPK1TDP1
SCHEMBL30598814 0.81 HSP90AA1 (0.34) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785696-B2 Phosphorus compound and method for preparing the same CHANGCHUN PLASTICS CO., LTD. (TW) 2014-07-22 US disclosed
US-20100125154-A1 PHOSPHORUS COMPOUND AND METHOD FOR PREPARING THE SAME CHANG CHUN PLASTIC CO., LTD. (TW) 2010-05-20 US disclosed
EP-2186816-A1 Phosphorus compound and method for preparing the same Chang Chun Plastics Co., Ltd. (TW) 2010-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100125154-A1 PHOSPHORUS COMPOUND AND METHOD FOR PREPARING THE SAME PHOSPHO1, PFAS, PPA1 ESR1 1186/4885ESR2 2330/4885KEAP1 4860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.