Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.58 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354791 | 0.85 | PTGS1 (1.00) | PTGS1ALOX15TSHRCASP1NPSR1 | |
| SCHEMBL29151281 | 0.85 | PTGS1 (1.00) | PTGS1ALOX15TSHRCASP1NPSR1 | |
| SCHEMBL25223673 | 0.81 | PTGS1 (0.62) | MEN1RAB9AKMT2APTGS1ALOX15 | |
| SCHEMBL3249395 | 0.81 | NPC1 (0.70) | MEN1NPC1RAB9AKMT2ARXFP1 | |
| SCHEMBL14082706 | 0.81 | MEN1 (0.55) | MEN1NPC1RAB9AKMT2ARXFP1 | |
| SCHEMBL3183924 | 0.81 | KMT2A (0.74) | MEN1NPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL29151324 | 0.81 | PTGS1 (0.67) | NPC1RAB9AKMT2ARXFP1PTGS1 | |
| SCHEMBL30354767 | 0.81 | PTGS1 (0.67) | NPC1RAB9AKMT2ARXFP1PTGS1 | |
| SCHEMBL30362498 | 0.80 | ALOX15 (0.72) | NPC1RAB9APTGS1ALOX15TSHR | |
| SCHEMBL3768771 | 0.80 | NPC1 (0.81) | MEN1NPC1RAB9AKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |