Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.59 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.59 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.59 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131146 | 0.85 | RAB9A (0.78) | NPSR1PTGS1TLR7LMNANPC1 | |
| SCHEMBL20526139 | 0.83 | NPC1 (0.56) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL30362429 | 0.81 | MEN1 (0.72) | TSHRLMNANPC1RAB9AKCNK3 | |
| SCHEMBL3246039 | 0.80 | MEN1 (0.75) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL30354791 | 0.80 | PTGS1 (1.00) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL29151281 | 0.80 | PTGS1 (1.00) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL1968503 | 0.80 | ALOX15 (0.60) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL18094556 | 0.80 | TLR7 (0.55) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL1464168 | 0.80 | KMT2A (0.69) | LMNANPC1RAB9AMAPTPOLB | |
| SCHEMBL1767502 | 0.79 | LMNA (0.59) | ALOX15TSHRCASP1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843858-B | Certain chemical entities, compositions and methods | 润新生物公司 | 2023-05-05 | — | — | CN | disclosed |