SCHEMBL3246192

SCHEMBL3246192

CC(C)(N=C=S)c1cccc(C(C)(C)N=C=S)c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GAA P10253 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26965552 0.87 CYP19A1 (0.36) MIF
SCHEMBL8763183 0.84 MIF (0.39) MIFESR1ESR2
SCHEMBL6675119 0.81 MIF (0.31) MIFGABRA1GABRB2
SCHEMBL34924 0.78 ESR1 (0.36) ESR1ESR2GAAGABRA1GABRB2
SCHEMBL10018065 0.77 HDAC8 (0.41) ESR1ESR2GAAGABRA1GABRB2
SCHEMBL3796067 0.77 MIF (0.38) MIF
SCHEMBL3796070 0.75 THRB (0.36)
SCHEMBL8763192 0.75 PDE2A (0.32)
Carbimide SCHEMBL4253887 0.74 ESR1 (0.33) ESR1ESR2GAAHDAC4HDAC2
SCHEMBL12050426 0.74 ESR1 (0.33) ESR1ESR2GAAHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO claimed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US claimed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO claimed
EP-2660609-B1 ROTARY SPEED DETECTION METHOD AND DEVICE THEREFOR, REACTION LIQUID VISCOSITY DETECTION METHOD AND DEVICE THEREFOR, AND METHOD FOR MANUFACTURING REACTION PRODUCT DAINIPPON INK & CHEMICALS (JP) 2016-03-16 EP disclosed
US-8781761-B2 Rotary speed detection method and device therefor, reaction liquid viscosity detection method and device therefor, and method for manufacturing reaction product DIC CORPORATION (JP) 2014-07-15 US disclosed
EP-2660609-A1 ROTARY SPEED DETECTION METHOD AND DEVICE THEREFOR, REACTION LIQUID VISCOSITY DETECTION METHOD AND DEVICE THEREFOR, AND METHOD FOR MANUFACTURING REACTION PRODUCT DIC Corporation (JP) 2013-11-06 EP disclosed
US-20130172507-A1 ROTARY SPEED DETECTION METHOD AND DEVICE THEREFOR, REACTION LIQUID VISCOSITY DETECTION METHOD AND DEVICE THEREFOR, AND METHOD FOR MANUFACTURING REACTION PRODUCT DIC CORPORATION (JP) 2013-07-04 US disclosed
US-20130158111-A1 Compositions and Methods for Depleting Mutant p53 GEORGETOWN UNIVERSITY (US) 2013-06-20 US disclosed
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO disclosed
EP-1319966-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-05-26 EP disclosed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US disclosed
US-7009031-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2006-03-07 US disclosed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO disclosed
US-20040024165-A1 Composition for optical material MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-02-05 US disclosed
EP-1319966-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-06-18 EP disclosed