Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494913 | 0.96 | ESR1 (0.33) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL34924 | 0.94 | ESR1 (0.36) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL12050426 | 0.89 | ESR1 (0.33) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL39076 | 0.89 | HDAC8 (0.43) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL24833769 | 0.87 | PGK1 (0.32) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL14065407 | 0.86 | ESR1 (0.30) | ESR1ESR2 | |
| SCHEMBL18126139 | 0.85 | ESR1 (0.32) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL14473846 | 0.85 | ESR1 (0.32) | ESR1ESR2GAAHDAC4HDAC2 | |
| SCHEMBL11535151 | 0.85 | CES2 (0.42) | GAA | |
| SCHEMBL13703565 | 0.85 | ESR1 (0.32) | ESR1ESR2GAAHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498379-B2 | Carbodiimides containing urea groups and silyl-groups | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20080015294-A1 | Carbodiimides Containing Urea Groups and Silane Groups | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015294-A1 | Carbodiimides Containing Urea Groups and Silane Groups | HRH4, HRH3, OXER1 | ESR1 2914/4885ESR2 1786/4885GAA 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.