Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.57 |
| ▸ | CES1 | P23141 | 8/20 | 0.57 |
| ▸ | CES2 | O00748 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL4658910 | 1.00 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Trimethylammonium SCHEMBL1711942 | 1.00 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Trimethylammonium SCHEMBL25400813 | 0.89 | FAAH (0.65) | FAAHCES1MEN1KMT2AHSD17B10 | |
| Dimethylamine SCHEMBL745789 | 0.87 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL12749827 | 0.83 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL12749833 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22033669 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22033577 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL29069456 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL724408 | 0.82 | FAAH (0.52) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247493-A1 | METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR IMMUNOTHERAPY BY DIRECT TUMOR INJECTION | PDS Biotechnology Corporation (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109391-A1 | METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR IMMUNOTHERAPY BY DIRECT TUMOR INJECTION | PDS BIOTECHNOLOGY CORPORATION (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-3720423-A1 | METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR STIMULATING TYPE 1 INTERFERON GENES | PDS Biotechnology Corporation (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113200-A1 | METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR STIMULATING TYPE 1 INTERFERON GENES | PDS BIOTECHNOLOGY CORPORATION (US) | 2019-06-13 | — | — | WO | disclosed |
| WO-2018067822-A1 | METHODS TO ALTER THE TUMOR MICROENVIRONMENT FOR EFFECTIVE CANCER IMMUNOTHERAPY | PDS BIOTECHNOLOGY CORPORATION (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2010086864-A1 | METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE | GALMED INTERNATIONAL LTD. (MT) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010009186-A1 | LIPOSOME FORMULATION HAVING HYDROPHILIC AND HYDROPHOBIC PHARMACEUTICAL COMPOUNDS CO-ENCAPSULATED THEREIN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-01-21 | — | — | WO | disclosed |
| US-20050169979-A1 | Liposomal vaccine | RECEPTOR BIOLOGIX, INC. | 2005-08-04 | — | — | US | disclosed |