Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.57 |
| ▸ | CES1 | P23141 | 8/20 | 0.57 |
| ▸ | CES2 | O00748 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL3246194 | 0.87 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Trimethylammonium SCHEMBL4658910 | 0.87 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Trimethylammonium SCHEMBL1711942 | 0.87 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Dimethylamine SCHEMBL12980876 | 0.83 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| Dimethylamine SCHEMBL5538214 | 0.83 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL12749827 | 0.83 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL29069456 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22033669 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22033577 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL12749833 | 0.83 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012167144-A1 | NANOCOATINGS FOR BIOLOGICAL MATERIALS | PAXVAX, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| EP-2430168-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND COLIPIDS FOR DELIVERING THERAPEUTICS MOLECULES | Cui, Kunyuan (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2011084721-A2 | CATIONIC MOLECULE AND METHOD OF USE | AGAVE PHARMA INC (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2010135207-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND COLIPIDS FOR DELIVERING THERAPEUTICS MOLECULES | AGAVE PHARMA, INCORPORATED (US) | 2010-11-25 | — | — | WO | disclosed |