Sugi Predict

Sugi Predict / Compounds / SCHEMBL324626

SCHEMBL324626

SCHEMBL324626

CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OXTR P30559 9/20 0.70
▸ AVPR1B P47901 2/20 0.63
▸ AVPR2 P30518 1/20 0.63
▸ AVPR1A P37288 1/20 0.63
▸ SSTR4 P31391 9/20 0.54
▸ SSTR2 P30874 8/20 0.54
▸ SSTR3 P32745 8/20 0.54
▸ SSTR5 P35346 8/20 0.54
▸ SSTR1 P30872 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14060519 1.00 OXTR (0.70) OXTRAVPR1BAVPR2AVPR1ASSTR4
SCHEMBL15510980 1.00 OXTR (0.70) OXTRAVPR1BAVPR2AVPR1ASSTR4
SCHEMBL13827825 1.00 OXTR (0.70) OXTRAVPR1BAVPR2AVPR1ASSTR4
SCHEMBL15511844 0.88 AVPR1B (0.68) OXTRAVPR1BAVPR2AVPR1ASSTR4
SCHEMBL14008026 0.87 OXTR (0.73) OXTRAVPR1BAVPR2AVPR1A
SCHEMBL22333523 0.86 OXTR (0.68) OXTRAVPR1BAVPR2AVPR1A
SCHEMBL22333508 0.86 OXTR (0.77) OXTRAVPR1BAVPR2AVPR1A
SCHEMBL15512193 0.83 OXTR (0.80) OXTRAVPR1BAVPR2AVPR1A
SCHEMBL13827822 0.82 OXTR (0.51) OXTRAVPR1BAVPR2AVPR1ASSTR4
SCHEMBL15511961 0.82 OXTR (0.88) OXTRAVPR1BAVPR2AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1414967-B1 GENE ASSOCIATED WITH LEISHMANIA PARASITE VIRULENCE PASTEUR INSTITUT TUNIS (TN) 2015-04-15 — — EP claimed
US-20140378668-A1 Tyrosine Bioconjugation through Aqueous Ene-Like Reactions SCRIPPS RESEARCH INST (US) 2014-12-25 — — US claimed
US-8715697-B2 Genes associated with Leishmania parasite virulence INSTITUT PASTEUR DE TUNIS (TN) 2014-05-06 — — US claimed
US-20120289682-A1 Tyrosine Bioconjugation through Aqueous Ene-Like Reactions THE SCRIPPS RESEARCH INSTITUTE 2012-11-15 — — US claimed
EP-2515914-A1 TYROSINE BIOCONJUGATION THROUGH AQUEOUS ENE-LIKE REACTIONS The Scripps Research Institute (US) 2012-10-31 — — EP claimed
WO-2011079315-A1 TYROSINE BIOCONJUGATION THROUGH AQUEOUS ENE-LIKE REACTIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2011-06-30 — — WO claimed
CN-101274960-A Genes associated with leishmania parasite virulence PASTEUR INSTITUT TUNIS (TN) 2008-10-01 — — CN claimed
US-20080199496-A1 Genes Associated with Leishmania Parasite Virulence INSTITUT PASTEUR DE TUNIS 2008-08-21 — — US claimed
US-20050119460-A1 Protein disulfide-isomerase for use as tool in detection, prevention and treatment of leishmaniasis; antiprotozoa agents INSTITUT PASTEUR DE TUNIS (TN) 2005-06-02 — — US claimed
CN-1526017-A Genes associated with leishmania parasite virulence О 2004-09-01 — — CN claimed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
US-20210205415-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC 2021-07-08 — — US disclosed
US-10772934-B2 Highly active polypeptides and methods of making and using the same LONGEVITY BIOTECH, INC. (US) 2020-09-15 — — US disclosed
US-20180193422-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2018-07-12 — — US disclosed
US-9932365-B2 Protein labeling with cyanobenzothiazole conjugates PROMEGA CORPORATION (US) 2018-04-03 — — US disclosed
US-5945033-A ALBUMIN, HEMOGLOBIN MIXTURE; STABILITY HEMOSPHERE, INC. (US) 1999-08-31 — — US disclosed
EP-0831793-A1 PROTEIN PARTICLES FOR THERAPEUTIC AND DIAGNOSTIC USE HEMOSPHERE, INC. (US) 1998-04-01 — — EP disclosed
US-5725804-A ALBUMIN PARTICLES STABLE TO RESOLUBILIZATION, POLYOXYETHYLENE GLYCOL, ALCOHOL HEMOSPHERE, INC. (US) 1998-03-10 — — US disclosed
US-5616311-A AQUEOUS ALBUMIN SUSPENSION STABILIZED BY HEMOGLOBIN PARTICLES HEMOSPHERE, INC. (US) 1997-04-01 — — US disclosed
WO-1996039128-A1 PROTEIN PARTICLES FOR THERAPEUTIC AND DIAGNOSTIC USE HEMOSPHERE, INC. (US) 1996-12-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180193422-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR OXTR 276/4885AVPR1B 588/4885AVPR2 753/4885
US-20210205415-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR OXTR 276/4885AVPR1B 588/4885AVPR2 753/4885
US-10772934-B2 Highly active polypeptides and methods of making and using the same SCTR, GIPR, APLNR OXTR 276/4885AVPR1B 588/4885AVPR2 753/4885
US-20140378668-A1 Tyrosine Bioconjugation through Aqueous Ene-Like Reactions TYR, DNPEP, TH OXTR 2299/4885AVPR1B 1709/4885AVPR2 2497/4885
US-20120289682-A1 Tyrosine Bioconjugation through Aqueous Ene-Like Reactions TYR, DNPEP, TH OXTR 2299/4885AVPR1B 1709/4885AVPR2 2497/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR OXTR 276/4885AVPR1B 588/4885AVPR2 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.