Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251459 | 1.00 | MAPT (0.43) | MAPTSMN1; SMN2KDM4ERELATDP1 | |
| SCHEMBL3248724 | 0.91 | RELA (0.39) | MAPTKDM4ERELATDP1NPSR1 | |
| SCHEMBL3249450 | 0.91 | RELA (0.39) | MAPTKDM4ERELATDP1NPSR1 | |
| SCHEMBL12311088 | 0.91 | RELA (0.39) | MAPTKDM4ERELATDP1NPSR1 | |
| SCHEMBL14132223 | 0.90 | NPSR1 (0.45) | MAPTKDM4ERAB9ANPSR1MEN1 | |
| SCHEMBL16315810 | 0.86 | MAPT (0.38) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL12311090 | 0.86 | NPSR1 (0.38) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL12905382 | 0.86 | NPSR1 (0.38) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL14132075 | 0.86 | MAPT (0.38) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL3246840 | 0.86 | MAPT (0.40) | MAPTSMN1; SMN2KDM4ETDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747774-B1 | Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres | OREAL (FR) | 2010-05-05 | — | — | EP | claimed |
| US-7585332-B2 | Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device | L'OREAL S.A. (FR) | 2009-09-08 | — | — | US | claimed |
| EP-2083790-A2 | DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS | L'Oreal (FR) | 2009-08-05 | — | — | EP | claimed |
| EP-2083923-A2 | COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE | L'Oreal (FR) | 2009-08-05 | — | — | EP | claimed |
| US-7399319-B2 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-07-15 | — | — | US | claimed |
| WO-2008043967-A2 | DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS | L'OREAL (FR) | 2008-04-17 | — | — | WO | claimed |
| WO-2008043968-A2 | COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE | L'OREAL (FR) | 2008-04-17 | — | — | WO | claimed |
| US-20070174977-A1 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-08-02 | — | — | US | claimed |
| EP-1747774-A1 | Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres | L'Oréal (FR) | 2007-01-31 | — | — | EP | claimed |
| WO-2010128214-A1 | TREATMENT OF COLORED FIBERS BY STYRYL OR IMINE COMPOUNDS IN THE PRESENCE OF ORGANIC OR INORGANIC ACIDS AND ZINC SALTS | L´OREAL (FR) | 2010-11-11 | — | — | WO | disclosed |
| EP-1747774-B1 | Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres | OREAL (FR) | 2010-05-05 | — | — | EP | disclosed |
| EP-2083923-B1 | COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE | OREAL (FR) | 2010-05-05 | — | — | EP | disclosed |
| US-7585332-B2 | Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device | L'OREAL S.A. (FR) | 2009-09-08 | — | — | US | disclosed |
| EP-2083923-A2 | COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE | L'Oreal (FR) | 2009-08-05 | — | — | EP | disclosed |
| US-20080189878-A1 | Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process | L'OREAL S.A. (FR) | 2008-08-14 | — | — | US | disclosed |
| US-7399319-B2 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-07-15 | — | — | US | disclosed |
| WO-2008043967-A2 | DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS | L'OREAL (FR) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043968-A2 | COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE | L'OREAL (FR) | 2008-04-17 | — | — | WO | disclosed |
| US-20070174977-A1 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-08-02 | — | — | US | disclosed |
| EP-1747774-A1 | Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres | L'Oréal (FR) | 2007-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080189878-A1 | Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process | KRT18, INHA, IK | MAPT 854/4885SMN1; SMN2 4299/4885KDM4E 1206/4885 |
| US-20070174977-A1 | Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers | KRT18, INHA, IK | MAPT 1182/4885SMN1; SMN2 2877/4885KDM4E 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.