SCHEMBL3248724

SCHEMBL3248724

CN(C)c1ccc(C=CC23OCCN2c2ccccc2C3(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RELA Q04206 1/20 0.39
▸ BCHE P06276 1/20 0.38
▸ MAPT P10636 8/20 0.36
▸ KDM4E B2RXH2 6/20 0.36
▸ APP P05067 5/20 0.36
▸ ALDH1A1 P00352 5/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ ALOX15 P16050 3/20 0.36
▸ TSHR P16473 3/20 0.36
▸ MAPK1 P28482 3/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ GLA P06280 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ TDP1 Q9NUW8 3/20 0.35
▸ HTT P42858 3/20 0.35
▸ NSD2 O96028 1/20 0.35
▸ SNCA P37840 1/20 0.34
▸ MEN1 O00255 4/20 0.34
▸ KMT2A Q03164 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3249450 1.00 RELA (0.39) RELABCHEMAPTKDM4EAPP
SCHEMBL12311088 1.00 RELA (0.39) RELABCHEMAPTKDM4EAPP
SCHEMBL3252614 0.93 NPSR1 (0.43) RELABCHEMAPTKDM4EAPP
SCHEMBL3240968 0.93 NPSR1 (0.43) RELABCHEMAPTKDM4EAPP
SCHEMBL12311093 0.93 NPSR1 (0.43) RELABCHEMAPTKDM4EAPP
SCHEMBL13963041 0.93 BCHE (0.39) RELABCHEMAPTKDM4EAPP
SCHEMBL3251459 0.91 MAPT (0.43) RELABCHEMAPTKDM4EALDH1A1
SCHEMBL3246701 0.91 MAPT (0.43) RELABCHEMAPTKDM4EALDH1A1
SCHEMBL14132223 0.89 NPSR1 (0.45) MAPTKDM4ENPSR1ALOX15TSHR
SCHEMBL14132075 0.88 MAPT (0.38) MAPTKDM4EALDH1A1NPSR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747774-B1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres OREAL (FR) 2010-05-05 — — EP claimed
US-7585332-B2 Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device L'OREAL S.A. (FR) 2009-09-08 — — US claimed
EP-2083790-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'Oreal (FR) 2009-08-05 — — EP claimed
EP-2083923-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'Oreal (FR) 2009-08-05 — — EP claimed
US-7399319-B2 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2008-07-15 — — US claimed
WO-2008043967-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'OREAL (FR) 2008-04-17 — — WO claimed
WO-2008043968-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'OREAL (FR) 2008-04-17 — — WO claimed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US claimed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP claimed
US-8437067-B2 Electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-05-07 — — US disclosed
US-20110019265-A1 DISPLAY ELEMENT AND METHOD OF FORMING POROUS LAYER IN DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-27 — — US disclosed
US-20110013261-A1 ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-20 — — US disclosed
WO-2010128214-A1 TREATMENT OF COLORED FIBERS BY STYRYL OR IMINE COMPOUNDS IN THE PRESENCE OF ORGANIC OR INORGANIC ACIDS AND ZINC SALTS L´OREAL (FR) 2010-11-11 — — WO disclosed
EP-1747774-B1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres OREAL (FR) 2010-05-05 — — EP disclosed
WO-2008043967-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'OREAL (FR) 2008-04-17 — — WO disclosed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US disclosed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US disclosed
US-7217500-B2 Color image-forming material and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-05-15 — — US disclosed
US-7217500-B2 Color image-forming material and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-05-15 — — US disclosed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers KRT18, INHA, IK RELA 2797/4885BCHE 1298/4885MAPT 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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