Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | CASP6 | P55212 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941351 | 0.98 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL157169 | 0.98 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL29518641 | 0.98 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL28471751 | 0.97 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| Water SCHEMBL7704455 | 0.97 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL9311654 | 0.92 | HSD17B10 (0.69) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL3373422 | 0.89 | TTR (0.71) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL8030849 | 0.89 | HSD17B10 (0.53) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL4113863 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL10703360 | 0.85 | TTR (0.65) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116273159-B | Sulfonated immobilized binary catalyst, preparation method and application thereof | 中国人民解放军军事科学院系统工程研究院 | 2023-11-17 | — | — | CN | claimed |
| CN-116273159-A | Sulfonated immobilized binary catalyst, preparation method and application thereof | 中国人民解放军军事科学院系统工程研究院 | 2023-06-23 | — | — | CN | claimed |
| CN-100595236-C | Preparation process of direct-blending navy D-R dye | WUJIANG MEIYAN SANYOU DYESTUFF CHEMICAL CO LTD | 2010-03-24 | — | — | CN | claimed |
| US-20090306132-A1 | USE OF DERIVATIVES OF NAPHTHALENESULPHONIC OR QUINOLINESULPHONIC ACID IN THE TREATMENT OF VASOPROLIFERATIVE OCULAR DISEASES | ITALFARMACO, S.A. (ES) | 2009-12-10 | — | — | US | claimed |
| US-20090076140-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | ITALFARMACO, S. A. (ES) | 2009-03-19 | — | — | US | claimed |
| EP-1994929-A1 | USE OF DERIVATIVES OF NAPHTHALENESULPHONIC OR QUINOLINESULPHONIC ACID IN THE TREATMENT OF VASOPROLIFERATIVE OCULAR DISEASES | ITALFARMACO, S.A. (ES) | 2008-11-26 | — | — | EP | claimed |
| CN-101307187-A | Preparation process of direct-blending navy D-R dye | WUJIANG MEIYAN SANYOU DYESTUFF (CN) | 2008-11-19 | — | — | CN | claimed |
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | ITALFARMACO, S.A. (ES) | 2006-07-20 | — | — | US | claimed |
| EP-1602644-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | Italfarmaco, S.A. (ES) | 2005-12-07 | — | — | EP | claimed |
| CN-116273159-B | Sulfonated immobilized binary catalyst, preparation method and application thereof | 中国人民解放军军事科学院系统工程研究院 | 2023-11-17 | — | — | CN | disclosed |
| CN-116273159-A | Sulfonated immobilized binary catalyst, preparation method and application thereof | 中国人民解放军军事科学院系统工程研究院 | 2023-06-23 | — | — | CN | disclosed |
| US-20160369237-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECH INC (US) | 2016-12-22 | — | — | US | disclosed |
| CN-102408743-B | Production process of direct blending navy blue D-R dye | WUJIANG MEIYAN SANYOU DYESTUFF CHEMICAL CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-102408743-A | Production process for directly blending navy D-R dye | WUJIANG MEIYAN SANYOU DYESTUFF CHEMICAL CO LTD | 2012-04-11 | — | — | CN | disclosed |
| WO-2004029017-A1 | NOVEL QUATERNARY AMMONIUM COMPOUNDS | COOEE BIOSCIENCES LIMITED (AU) | 2004-04-08 | — | — | WO | disclosed |
| EP-0799281-B1 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORP (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1225205-A2 | Carbon black reacted with diazonium salts and products | CABOT CORPORATION (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0558258-B1 | N-isoxazole-naphthylsulfonamide derivatives and their use as endothelin antagonists | SQUIBB & SONS INC (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5378715-A | Sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB CO. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0558258-A1 | N-isoxazole-naphthylsulfonamide derivatives and their use as endothelin antagonists | E.R. SQUIBB & SONS, INC. (US) | 1993-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306132-A1 | USE OF DERIVATIVES OF NAPHTHALENESULPHONIC OR QUINOLINESULPHONIC ACID IN THE TREATMENT OF VASOPROLIFERATIVE OCULAR DISEASES | NQO2, SQLE, SQOR | ALDH1A1 337/4885HSD17B10 1854/4885CASP6 553/4885 |
| US-20090076140-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES | SUCNR1, NR1H4, CYP2B6 | ALDH1A1 2229/4885HSD17B10 436/4885CASP6 2320/4885 |
| US-20060160849-A1 | Pharmaceutical compositions containing sulphonic acid derivatives | SUCNR1, NR1H4, CYP2B6 | ALDH1A1 2206/4885HSD17B10 429/4885CASP6 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.