Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251399 | 1.00 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL3247267 | 1.00 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL3251394 | 1.00 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3248417 | 0.99 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3248411 | 0.99 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL5746835 | 0.92 | KCNH2 (0.51) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL6079365 | 0.92 | KCNH2 (0.51) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL6079362 | 0.92 | KCNH2 (0.51) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL5746843 | 0.92 | KCNH2 (0.51) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL6079369 | 0.92 | KCNH2 (0.51) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181996-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2010-05-05 | — | — | EP | claimed |
| US-7312212-B2 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2007-12-25 | — | — | US | claimed |
| US-20050159411-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2005-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159411-A1 | Aminopiperidine derivatives | AMPD2, AMPD3, NPEPPS | KCNH2 1182/4885SLC2A1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.