Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170865 | 1.00 | NAAA (0.70) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL8355467 | 0.98 | NAAA (0.67) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL19630921 | 0.98 | NAAA (0.67) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL13300769 | 0.93 | NAAA (0.64) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL16357639 | 0.91 | NAAA (0.61) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL17172545 | 0.91 | NAAA (0.82) | NAAAKEAP1NFE2L2GNAI3GNAO1 | |
| SCHEMBL13432005 | 0.87 | NAAA (0.56) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1285234 | 0.85 | NAAA (0.54) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL23419143 | 0.85 | NAAA (0.58) | NAAAKEAP1NFE2L2ITGB3ITGA2B | |
| SCHEMBL61158 | 0.85 | NAAA (0.58) | NAAAKEAP1NFE2L2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490359-B1 | DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE | SENSORS FOR MED & SCIENCE INC (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-1490359-A4 | DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE | SENSORS FOR MED & SCIENCE INC (US) | 2006-08-23 | — | — | EP | disclosed |
| US-7078554-B2 | Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050043275-A1 | Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone | SENSEONICS, INCORPORATED | 2005-02-24 | — | — | US | disclosed |
| EP-1490359-A1 | DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE | Sensors for Medicine and Science, Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6800451-B2 | MORE STABLE REACTION OF GLUCOSE WITH A BORONIC ACID COMPOUND SUCH AS 9,10-BISN-(BORONOBENZYL)-N-(3-(METHYACRYLAMIDO) PROPYLAMINO)METHYLANTHRACENE | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2004-10-05 | — | — | US | disclosed |
| WO-2003078424-A1 | DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030082663-A1 | Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043275-A1 | Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone | GCK, KHK, HK1 | NAAA 2540/4885KEAP1 973/4885NFE2L2 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.