Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170865 | 0.98 | NAAA (0.70) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL3247411 | 0.98 | NAAA (0.70) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL19630921 | 0.96 | NAAA (0.67) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL13300769 | 0.94 | NAAA (0.64) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL16357639 | 0.92 | NAAA (0.61) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL13432005 | 0.89 | NAAA (0.56) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL17172545 | 0.88 | NAAA (0.82) | NAAAKEAP1NFE2L2EPHX1GNAI3 | |
| Hydrochloric Acid SCHEMBL1285234 | 0.87 | NAAA (0.54) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL23419143 | 0.86 | NAAA (0.58) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 | |
| SCHEMBL61158 | 0.86 | NAAA (0.58) | NAAAKEAP1NFE2L2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385870-B1 | PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2003062265-A2 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |