SCHEMBL3247440

SCHEMBL3247440

O=S(=O)(O)C1NCCc2[c]cccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28063035 0.73 TSHR (0.55) TSHRNPSR1
SCHEMBL4509951 0.73 TSHR (0.41) TSHRNPSR1
SCHEMBL17674655 0.72 MAOA (0.39) TSHR
Hydrochloric Acid SCHEMBL4520525 0.72 TSHR (0.43) TSHRNPSR1
Hydrochloric Acid SCHEMBL4506034 0.72 TSHR (0.43) TSHRNPSR1
SCHEMBL1403725 0.63 POLL (0.36)
SCHEMBL9056308 0.62 SRC (0.36)
SCHEMBL27562414 0.61 ALDH1A1 (0.32)
SCHEMBL11498386 0.61 PRCP (0.50) TSHRNPSR1
SCHEMBL1345184 0.60 HTR2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227803-B1 COMPOUNDS FOR INHIBITING IAPP-ASSOCIATED AMYLOID DEPOSITS BELLUS HEALTH INTERNATIONAL LTD (CH) 2010-05-05 EP claimed