Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.61 |
| ▸ | FYN | P06241 | 4/20 | 0.61 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.55 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183190 | 0.91 | BRAF (0.71) | BRAFFYNPIP4K2APIP4K2BABL1 | |
| SCHEMBL3244837 | 0.85 | FYN (0.57) | BRAFFYNSYK | |
| SCHEMBL3247802 | 0.83 | BRAF (0.58) | BRAFFYNSYKABL1 | |
| SCHEMBL13170081 | 0.82 | L3MBTL1 (0.64) | FYNMTNR1AMTNR1B | |
| SCHEMBL4195750 | 0.82 | BRAF (0.65) | BRAFFYNPIP4K2APIP4K2B | |
| SCHEMBL4191864 | 0.81 | BRAF (0.70) | BRAFFYNPIP4K2APIP4K2B | |
| SCHEMBL4194542 | 0.80 | BRAF (0.62) | BRAFFYNPIP4K2APIP4K2B | |
| SCHEMBL4198997 | 0.80 | BRAF (0.72) | BRAFFYNPIP4K2APIP4K2BMTNR1A | |
| SCHEMBL4191746 | 0.79 | BRAF (0.68) | BRAFFYNPIP4K2APIP4K2B | |
| SCHEMBL4194092 | 0.77 | BRAF (0.65) | BRAFFYNPIP4K2APIP4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |