Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 13/20 | 0.57 |
| ▸ | SRC | P12931 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249341 | 0.91 | ROCK2 (0.59) | ROCK2SRCROCK1KDRCDC42BPA | |
| SCHEMBL3248059 | 0.91 | ROCK2 (0.57) | ROCK2SRCROCK1KDRCDC42BPA | |
| SCHEMBL3242746 | 0.89 | ROCK2 (0.58) | ROCK2ROCK1KDRCDC42BPA | |
| SCHEMBL3129438 | 0.84 | ROCK2 (0.68) | ROCK2ROCK1KDRCDC42BPA | |
| SCHEMBL3241420 | 0.83 | ROCK2 (0.59) | ROCK2ROCK1KDRCDC42BPA | |
| SCHEMBL3247570 | 0.83 | ROCK2 (0.57) | ROCK2ROCK1KDRCDC42BPA | |
| SCHEMBL3246082 | 0.82 | ROCK2 (0.61) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL13390977 | 0.80 | ROCK2 (0.57) | ROCK2SRCROCK1KDRCDC42BPA | |
| SCHEMBL3251367 | 0.79 | ROCK2 (0.49) | ROCK2ROCK1KDRCDC42BPAHTR2A | |
| SCHEMBL10132803 | 0.79 | SRC (0.57) | ROCK2SRCROCK1KDRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |